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Effects of compounds acting on GABAB receptors in the pentylenetetrazole kindling model of epilepsy in mice

✍ Scribed by Giovambattista De Sarro; Ernesto Palma; Nicola Costa; Rosario Marra; Santo Gratteri; Angela De Sarro; Domenicantonio Rotiroti

Book ID
117186978
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
698 KB
Volume
39
Category
Article
ISSN
0028-3908

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Anticonvulsant effect of felbamate in the pentylenetetrazole kindling model of epilepsy in the rat
✍ O. Giorgi; G. Carboni; V. Frau; M. Orlandi; V. Valentini; A. Feldman; M. G. Cord πŸ“‚ Article πŸ“… 1996 πŸ› Springer-Verlag 🌐 English βš– 661 KB

The present study was designed to examine the ability of felbamate, a novel antiepileptic agent, to antagonize the increase in seizure severity (i.e., chemical kindling) produced by chronic treatment with initially subconvulsant doses of pentylenetetrazol (PTZ). Rats were treated with PTZ (30 mg/kg,