𝔖 Bobbio Scriptorium
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The pathogenesis and imaging of the tuberous sclerosis complex

✍ Scribed by Henry J. Baskin


Book ID
105940990
Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
872 KB
Volume
38
Category
Article
ISSN
0301-0449

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## Abstract Soon after proposing the β€œtwo‐hit” hypothesis for tumorigenesis, Knudson pursued further experimental validation of the concept by using a rat model of dominantly inherited renal tumor. Today, the Eker rat is one of the best characterized models of tuberous sclerosis complex (TSC) and h