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Tuberous Sclerosis Complex and the Ketogenic Diet

✍ Scribed by Eric H. Kossoff; Elizabeth A. Thiele; Heidi H. Pfeifer; Jane R. McGrogan; John M. Freeman


Book ID
109108485
Publisher
Wiley (Blackwell Publishing)
Year
2005
Tongue
English
Weight
47 KB
Volume
46
Category
Article
ISSN
0013-9580

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## Abstract Soon after proposing the β€œtwo‐hit” hypothesis for tumorigenesis, Knudson pursued further experimental validation of the concept by using a rat model of dominantly inherited renal tumor. Today, the Eker rat is one of the best characterized models of tuberous sclerosis complex (TSC) and h