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The partial structure of LL-AV290 - a new antibiotic

✍ Scribed by Joseph J. Hlavka; Panayota Bitha; James H. Boothe; George Morton

Publisher
Elsevier Science
Year
1974
Tongue
French
Weight
202 KB
Volume
15
Category
Article
ISSN
0040-4039

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✦ Synopsis

Previous communications 192 from these Laboratories have described the isolation and characterization of a new antibiotic, designated as LL AV290, that exhibited both in viva and in vitro activity against gram positive bacteria. We now wish to report some results on the partial structure of this antibiotic.tt Initial degradative studies1 indicated this material to be a glycopeptide with some structural similarities to both vancomycin3 and the ristocetins. 4 Elemental analysis 1 on LL AV290 indicated the presence of carbon, hydrogen, nitrogen, chlorine and N-alkyl.

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