The oxidative macrocyclization of phenolic peptides. A biomimetic approach to the synthesis of the vancomycin family of antibiotics
β Scribed by Evans, David A.; Ellman, Jonathan A.; DeVries, Keith M.
- Book ID
- 121472447
- Publisher
- American Chemical Society
- Year
- 1989
- Tongue
- English
- Weight
- 356 KB
- Volume
- 111
- Category
- Article
- ISSN
- 0002-7863
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
The bis-diaryl ether cross-linked amino acid fragment, which constitutes the upper part of a vancomycin aglycone framework, was synthesized for the first time using an enzymatic oxidative phenolic coupling methodology. This was achieved via two peroxidase-catalyzed reactions of three amino acid deri