𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The ontogeny of L-α-hydroxyacid oxidase isozymes in the mouse

✍ Scribed by Miles, Joanna L. ;Holmes, Roger S.

Book ID
102336109
Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
304 KB
Volume
192
Category
Article
ISSN
0022-104X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Mouse liver hydroxyacid oxidase isozymes are present at low levels at birth and increase inactivity until day 13 after which HAOX‐B almost disappears and HAOX‐A i s reduced to approximately one half the maximum level in the adult. Kidney HAOX‐G appears near day 13 post partum and increases until adultl evels are reached, the female having four times the activity of the male. The pregnant female has significantly lower levels of HAOX‐A and HAOX‐B in the liver and higher activity ofHAOX‐B in the kidney. Developmental changes occur in the extent of epigenetic modification of mouse liver HAOX‐A during theearly neonatal period.

📜 SIMILAR VOLUMES

Genetics and ontogeny of aldehyde dehydr
Genetics and ontogeny of aldehyde dehydrogenase isozymes in the mouse: Localization ofAhd-1 encoding the mitochondrial isozyme on chromosome 4
✍ Roger S. Holmes 📂 Article 📅 1978 🏛 Springer 🌐 English ⚖ 493 KB

Electrophoretic variants for the mitochondrial isozyme of aldehyde dehydrogenase (AHD) have been observed in inbred strains and in Harwell linkage testing stocks of Mus musculus. F1 (LVC X C57BL/Go) mice showed a codominant allele three-bounded phenotype, which suggests a dimeric subunit structure (

Genetics and ontogeny of aldehyde dehydr
Genetics and ontogeny of aldehyde dehydrogenase isozymes in the mouse: Evidence for a locus controlling the inducibility of the liver microsomal isozyme
✍ Glenn P. Timms; Roger S. Holmes 📂 Article 📅 1981 🏛 Springer 🌐 English ⚖ 611 KB

Variation in the inducibility of the liver microsomal isozyme of aldehyde dehydrogenase (designated AHD-Cy) by phenobarbital administration was observed among inbred strains and linkage testing stocks of Mus musculus. The phenotypes were inherited in a normal Mendelian fashion with two alleles showi

Genetics of peroxisomal enzymes in the m
Genetics of peroxisomal enzymes in the mouse: Nonlinkage ofd-amino acid oxidase locus (Dao) to catalase (Cs) andl-α-hydroxyacid oxidase (Hao-1) loci on chromosome 2
✍ Roger S. Holmes 📂 Article 📅 1976 🏛 Springer 🌐 English ⚖ 373 KB

An electrophoretic polymorphism of the peroxisomal enzyme D-amino acid oxidase was observed in NZC strain Mus musculus. F1 (NZC X BALB/c) mice showed a codominant allcle two-banded phenotype which is inconsistent with the dimeric subunit structure reported for this enzyme in other species. The enzym