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The Nerve Growth Factor Receptor Gene is at Human Chromosome Region 17q12-17q22, Distal to the Chromosome 17 Breakpoint in Acute Leukemias

✍ Scribed by Kay Huebner, Masaharu Isobe, Moses Chao, Mark Bothwell, Alonzo H. Ross, Janet Finan, James A. Hoxie, Amita Sehgal, C. Randy Buck, Anthony Lanahan, Peter C. Nowell, Hilary Koprowski and Carlo M. Croce


Book ID
123632645
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
1014 KB
Volume
83
Category
Article
ISSN
0027-8424

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Insulin-like growth-factor-binding proteins (IGFBPs) constitute a family of structurally related proteins that specifically bind insulin-like growth factors and modulate their functions. In this study, the chromosomal localization was determined for the gene encoding IGFBP4, i.e. inhibitory-IGFBP. A