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The nature of benzo[a]pyrene binding to DNA in an epithelial cell culture system

✍ Scribed by C.B. Wigley; M.H. Thompson; P. Brookes


Book ID
113145687
Publisher
Elsevier Science
Year
1976
Weight
237 KB
Volume
12
Category
Article
ISSN
0014-2964

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The role of 9-hydroxybenzo(a)pyrene in t
✍ H. W. S. King; M. H. Thompson; P. Brookes πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 French βš– 523 KB

## Abstract A study of the liver microsome‐mediated binding to added DNA of the phenol metabolites of benzo (a)‐pyrene (BP‐OH) and of 7,8‐dihydro‐7,8‐dihydroxybenzo (a)pyrene (BP‐7,8‐diol) suggested that as in the case of BP itself the reaction was catalysed by the enzyme aryl hydrocarbon hydroxyla