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Effects of pretreatment with benzo[a]pyrene on the stereochemical selectivity of metabolic activation of benzo[a]pyrene to DNA-binding metabolites in hamster embryo cell cultures

✍ Scribed by Teresa A. Smolarek; Stephanie L. Morgan; Jeffry Kelley; William M. Baird


Book ID
113137025
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
687 KB
Volume
64
Category
Article
ISSN
0009-2797

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The relation of metabolism to macromolec
✍ Margaret E. Duncan; P. Brookes πŸ“‚ Article πŸ“… 1970 πŸ› John Wiley and Sons 🌐 French βš– 610 KB

## Abstract The metabolism of tritiated benzo[a]pyrene (B[a]P) by primary mouse embryo cells in culture was studied. At concentrations of B[a]P in the medium below about 2–3 mΞΌ moles/ml, metabolism was exponential with time, but at higher concentrations a period of rapid metabolism was followed by