The natural killer cell
โ Scribed by Jeffrey R. Dawson
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 134 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0167-5699
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Natural killer (NK) cell tumors are an uncommon and heterogeneous group of disorders. The World Health Organization (WHO) classified mature NK cell neoplasms into 2 types: 1) extranodal NK cell lymphoma, nasal type and 2) aggressive NK cell leukemia. The mature NK cell tumors are preval
The specificity in the recognition of hematopoietic target cells by natural killer cells is primarily provided by inhibitory receptors and several such receptors have been identified in the past year. Surprisingly, the recognition of MHC class I molecules by inhibitory receptors on human natural kil
In killing of cellular targets, natural killer cells employ receptors that activate them and receptors specific for MHC class I that inhibit their activation. Progress in understanding the inhibitory receptors has been rapid, and indications are that they fall into two distinct structural types that
Although the antigen-specific receptors of T and B lymphocytes have been characterized, the receptors used by natural killer cells to recognize normal cells, tumors, and virus-infected cells have remained elusive. Recently, experimental systems have been developed to identify these structures, and c