𝔖 Bobbio Scriptorium
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Natural killer cell receptors

✍ Scribed by Wayne M Yokoyama


Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
895 KB
Volume
10
Category
Article
ISSN
0952-7915

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✦ Synopsis


In killing of cellular targets, natural killer cells employ receptors that activate them and receptors specific for MHC class I that inhibit their activation. Progress in understanding the inhibitory receptors has been rapid, and indications are that they fall into two distinct structural types that appear to utilize the same inhibitory signaling cascade; meanwhile, components of the activation cascade are being elucidated, permitting us to integrate the pathways involved.


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