𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Natural killer cell receptors

✍ Scribed by Eric O Long; Nicolai Wagtmann

Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
622 KB
Volume
9
Category
Article
ISSN
0952-7915

No coin nor oath required. For personal study only.

✦ Synopsis

The specificity in the recognition of hematopoietic target cells by natural killer cells is primarily provided by inhibitory receptors and several such receptors have been identified in the past year. Surprisingly, the recognition of MHC class I molecules by inhibitory receptors on human natural killer cells involves two different types of receptors, one with Ig domains (killer cell inhibitory receptor), and another with C-type lectin domains (CD94-NKG2). Mouse natural killer cells recognize MHC class I molecules through the C-type lectin Ly49 receptors but also express a receptor, of unknown ligand specificity, that is related to the killer cell inhibitory receptor.

πŸ“œ SIMILAR VOLUMES

Natural killer cell receptors
Natural killer cell receptors
✍ Wayne M Yokoyama πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 1024 KB
Natural killer cell receptors
Natural killer cell receptors
✍ Wayne M Yokoyama πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 English βš– 895 KB

In killing of cellular targets, natural killer cells employ receptors that activate them and receptors specific for MHC class I that inhibit their activation. Progress in understanding the inhibitory receptors has been rapid, and indications are that they fall into two distinct structural types that

Candidate natural killer cell receptors
Candidate natural killer cell receptors
✍ Erhard Hofer; Markus DΓΌchler; Susan A. Fuad; Jeffrey P. Houchins; Toshio Yabe; F πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science 🌐 English βš– 215 KB