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The natural history of lymphocyte subsets in the peripheral lymphoid organs and pancreas in the non-obese diabetic (NOD) mouse

✍ Scribed by Bacelj, Angela; Burkhardt, Klaus; Mandel, Thomas E.


Book ID
123099143
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
171 KB
Volume
3
Category
Article
ISSN
0896-8411

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We investigate the role played by dendritic cells (DCs) in the non-obese diabetic (NOD) mouse pancreas. The early peri-islet, nondestructive infiltration phase, and intra-islet, destructive infiltration phase, which immediately precedes overt diabetes, are studied. Results show that infiltrating cel