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The molecular structure of N-hydroxyurea

✍ Scribed by Gianfranco La Manna; Giampaolo Barone

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
208 KB
Volume
57
Category
Article
ISSN
0020-7608

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✦ Synopsis

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Ab initio calculations were performed on the tautomers and conformers of N-hydroxyurea using a 6-31~** basis set. The minimum-energy structures have been found and the importance of the intramolecular hydrogen bond as the stabilizing factor was pointed out.

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N-hydroxysulfamides as analog of N-hydro
N-hydroxysulfamides as analog of N-hydroxyurea: synthesis and biological evaluation
✍ A.-Houssem Hajri; Georges Dewynter; Marc Criton; Pierre Dilda; Jean-Louis Monter πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 82 KB πŸ‘ 1 views

A series of sulfa-analog of hydroxyurea, derived from N-hydroxysulfamide H 2 NSO 2 NHOH, were synthesized starting from chlorosulfonyl isocyanate (CSI) and O-substituted hydroxylamines. Their antiproliferative, antiviral (in synergy with ddI), and antifungal activities have been evaluated.