The Mitsunobu Reaction: An Alternative Synthesis of 1-(Primary Alkyl)benzotriazoles
β Scribed by Katritzky, Alan R.; Oniciu, Daniela C.; Ghiviriga, Ion
- Book ID
- 126744685
- Publisher
- Taylor and Francis Group
- Year
- 1997
- Tongue
- English
- Weight
- 293 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0039-7911
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π SIMILAR VOLUMES
## Abstract 1β(Benzotriazolβ1βyl)alkyl esters 2aβu were obtained in yields averaging 86% by the direct reaction of various aldehydes with the corresponding __N__βacylbenzotriazoles in the presence of a catalytic amount of potassium carbonate (10β25 mole %). The procedure was optimized by evaluating
## Abstract The __Mitsunobu__ reaction is an important tool in carbocyclic nucleoside chemistry for the direct coupling of alcohols with heterocyclic bases under mild conditions. Chemical evidences for an unusual competitive __O__^2^β __vs. N__^1^βalkylation of 3βsubstituted pyrimidines is presente