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The metabolism of benzo(a)pyrene in rat liver microsomes: The effect of asbestos-associated metal ions and pH

✍ Scribed by Ruth Thomson; Ian Webster; T.A. Kilroe-Smith

Book ID
115873098
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
596 KB
Volume
7
Category
Article
ISSN
0013-9351

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✍ Ronald A. Lubet; Jorge Capdevila; Russell A. Prouoh πŸ“‚ Article πŸ“… 1979 πŸ› John Wiley and Sons 🌐 French βš– 473 KB πŸ‘ 1 views

## Abstract A rat liver microsome‐mediated bacterial mutagenicity test showed 9‐hydroxybenzo (__a__) pyrene to be significantly more effective as a pre‐mutagen than benzo (__a__) pyrene. Experiments measuring the ability of these compounds to be metabolically activated to moieties that alky late ex