𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The Meinwald Reaction of Alkyl Propionates. Synthesis of the C1—C9 Fragment of Aurisides.

✍ Scribed by Maria-Yolanda Rios; Francisco Velazquez; Horacio F. Olivo


Book ID
101955569
Publisher
John Wiley and Sons
Year
2003
Weight
134 KB
Volume
34
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


The Meinwald reaction of alkyl propionat
✍ Marı́a-Yolanda Rı́os; Francisco Velázquez; Horacio F Olivo 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 282 KB

The C1-C9 northern fragment of aurisides 12a was prepared in eight steps and 41% overall yield starting from Grieco's bicyclic lactone (þ)-4. The synthesis features a key stereoselective Meinwald reaction of the lithium enolate of alkyl propionate with the functionalized d-lactone 3.

Synthesis of a C1–C9 fragment of rhizoxi
✍ Richard J Davenport; Andrew C Regan 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 91 KB

A C1-C9 fragment of the antitumour macrolide rhizoxin has been synthesised. An Evans' asymmetric aldol reaction was used to set up the first two chiral centres, and an a,b-unsaturated d-lactone was then formed on the acyclic system by an intramolecular Wadsworth-Emmons reaction. Stereoselective hydr

Synthesis of C1C8 and C9C24 fragments
✍ Sandra A. Filla; Jinhua J. Song; Lihren Chen; Satoru Masamune 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 301 KB

The C1-C8 and C9--C24 fragments of (-)-discodermolide, the antipode of the marine natural product (+)discodermolide, have been synthesized with excellent stereoselectivities. These syntheses feature the utilization of the isoxazolidine-mediated asymmetric alkylation methodology and fragment-fragment