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The mechanism of the vicinal interchange reactions catalysed by coenzyme B12

✍ Scribed by Robert Hamilton; John J. Rooney


Publisher
Elsevier Science
Year
1982
Weight
279 KB
Volume
17
Category
Article
ISSN
0304-5102

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Functional ethanolamine ammonia-lyase is inactivated by N1O as well as by 0 +, indicating that the active form of coenzyme B, Z is an enzyme-bound corrin derivative in which the Co-C bond of the coenzyme is broken and the cobalt ion is in the +l state of oxidation. The nucleoside fragment formed in