We report a method based upon fast atom bombardment mass spectrometry (FAB-MS) and stable isotope dilution techniques for the measurement of urinary trimethylamine (TMA) and trimethylamine N-oxide (TMAOx). TMA is extracted from urine that was spiked with 15 N-labeled TMA. The extracted TMA isotopome
β¦ LIBER β¦
The measurement of dimethylamine, trimethylamine, and trimethylamine N-oxide using capillary gas chromatography-mass spectrometry
β Scribed by Kerry-Ann daCosta; J.James Vrbanac; Steven H. Zeisel
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 562 KB
- Volume
- 187
- Category
- Article
- ISSN
- 0003-2697
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## Abstract Key metabolites for the diagnosis of the genetic disorder trimethylaminuria are trimethylamine (TMA) and trimethylamine __N__βoxide (TMAO). A rapid, automatable flow injection ESIβMS/MS method for their measurement in urine has been developed. The TMA was derivatized with ethyl bromoace
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