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The management of pregnancy in paroxysmal nocturnal haemoglobinuria on long term eculizumab

✍ Scribed by Richard Kelly; Louise Arnold; Stephen Richards; Anita Hill; Charlotte Bomken; John Hanley; Andrew Loughney; Jon Beauchamp; Gus Khursigara; Russell P. Rother; Elizabeth Chalmers; Andrew Fyfe; Edward Fitzsimons; Ryotaro Nakamura; Anna Gaya; Antonio M. Risitano; Jörg Schubert; Derek Norfolk; Nigel Simpson; Peter Hillmen

Book ID
108676695
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
69 KB
Volume
149
Category
Article
ISSN
0007-1048

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✍ Peter Hillmen; Modupe Elebute; Richard Kelly; Alvaro Urbano-Ispizua; Anita Hill; 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 140 KB 👁 2 views

## Abstract Paroxysmal nocturnal hemoglobinuria (PNH) is a debilitating and life‐threatening disease in which lysis of PNH red blood cells frequently manifests with chronic hemolysis, anemia, and thrombosis. Renal damage in PNH is associated with chronic hemosiderosis and/or microvascular thrombosi