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Paroxysmal nocturnal hemoglobinuria (PNH) and pregnancy in the era of eculizumab

✍ Scribed by Alexey V. Danilov; Hedy Smith; Sabrina Craigo; Dianne M. Feeney; Valerie Relias; Kenneth B. Miller

Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
95 KB
Volume
33
Category
Article
ISSN
0145-2126

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## Abstract Paroxysmal nocturnal hemoglobinuria (PNH) is a debilitating and life‐threatening disease in which lysis of PNH red blood cells frequently manifests with chronic hemolysis, anemia, and thrombosis. Renal damage in PNH is associated with chronic hemosiderosis and/or microvascular thrombosi