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The isolation and preliminary characterization of somatic cell mutants resistant to the protein synthesis inhibitor—Emetine

✍ Scribed by Gupta, Radhey S.; Siminovitch, Louis


Book ID
122006458
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
525 KB
Volume
9
Category
Article
ISSN
0092-8674

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Isolation and genetical and biochemical
✍ L. Giudice; D. R. Massardo; F. Manna; K. Wolf 📂 Article 📅 1986 🏛 Springer-Verlag 🌐 English ⚖ 200 KB

Mutants resistant to 200 micrograms/ml of the alkaloid lycorine (LYCR) in non-fermentable substrate were isolated after nitrosoguanidine mutagenesis. Tetrad analysis and growth of heterozygous (LYCR/lycS) diploids from two different mutants revealed that a single nuclear and dominant mutation is res