The investigation of cancerous human bone (osteoclastoma) by small-angle X-ray scattering

✍ Scribed by Patel, A. ;Khanduala, B. Ch. ;Thakur, G. B. ;Labischinski, H.

• Publisher: John Wiley and Sons
• Year: 1983
• Weight: 390 KB
• Volume: 21
• Category: Article
• ISSN: 0360-6376
• DOI: 10.1002/pol.1983.170211008

✦ Synopsis

Abstract

Small‐angle X‐ray scattering methods were applied to provide a pore analysis of cancerous human bone (osteoclastoma). For experimental measurements of the scattering intensities a small‐angle Kratky camera, equipped with a counterattachment and a programmable step‐scanning device, was used. By applying the theories of Kratky, Porod, Debye, and Bueche, applicable to a densely packed two‐phase system belonging to a general micelle system, macromolecular parameters such as specific inner surface, length of coherence, range of inhomogeneity, void percentage, and transversal lengths l̄~1~ and l̄~2~ were evaluated and found to be 4.69 × 10^−4^ Å^−1^, 21.39 Å, 18.01 Å, 0.21%, 18.01 Å and 8.53 × 10^3^ Å, respectively. A comparison of these parameters with those of pure human bone revealed a macromolecular dissociation in osteoclastoma.