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The interleukin-6 -174promoter polymorphism is associated with long-term kidney allograft survival

✍ Scribed by Michael Müller-Steinhardt; Lutz Fricke; Brigitte Müller; Holger Kirchner; Christoph Härtel

Book ID
117414915
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
34 KB
Volume
63
Category
Article
ISSN
0198-8859

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The interleukin-6 -174promoter polymorph
The interleukin-6 -174promoter polymorphism is associated with long-term kidney allograft survival
✍ Müller-Steinhardt, Michael; Härtel, Christoph; Müller, Brigitte; Kirchner, Ho 📂 Article 📅 2002 🏛 Nature Publishing Group 🌐 English ⚖ 71 KB

## Background: Th1-dependent effector mechanisms may be responsible for allograft rejection. recently, interleukin-6 (il-6) has been shown to antagonize cd4+ t cells to effector th2 cells and, in the process, differentiate them into th1 cells. ## Methods: To assess the role of il-6 in long-term a