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Cooperative Influence of the Interleukin-6 Promoter Polymorphisms –597, –572 and –174 on Long-Term Kidney Allograft Survival

✍ Scribed by Michael Müller-Steinhardt; Lutz Fricke; Brigitte Müller; Brigitte Ebel; Holger Kirchner; Christoph Härtel


Book ID
114803046
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
72 KB
Volume
4
Category
Article
ISSN
1600-6135

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The interleukin-6 -174promoter polymorph
✍ Müller-Steinhardt, Michael; Härtel, Christoph; Müller, Brigitte; Kirchner, Ho 📂 Article 📅 2002 🏛 Nature Publishing Group 🌐 English ⚖ 71 KB

## Background: Th1-dependent effector mechanisms may be responsible for allograft rejection. recently, interleukin-6 (il-6) has been shown to antagonize cd4+ t cells to effector th2 cells and, in the process, differentiate them into th1 cells. ## Methods: To assess the role of il-6 in long-term a