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The interleukin-6 −174 promoter polymorphism is associated with extrapulmonary bacterial dissemination in Streptococcus pneumoniae infection

✍ Scribed by Bernhard Schaaf; Jan Rupp; Michael Müller-Steinhardt; Jan Kruse; Florian Boehmke; Matthias Maass; Peter Zabel; Klaus Dalhoff


Book ID
116397605
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
127 KB
Volume
31
Category
Article
ISSN
1043-4666

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## Background: Th1-dependent effector mechanisms may be responsible for allograft rejection. recently, interleukin-6 (il-6) has been shown to antagonize cd4+ t cells to effector th2 cells and, in the process, differentiate them into th1 cells. ## Methods: To assess the role of il-6 in long-term a