✦ LIBER ✦

The interleukin-4 family of lymphokines

✍ Scribed by Jean-Louis Boulay; William E. Paul

Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 705 KB
Volume: 4
Category: Article
ISSN: 0952-7915
DOI: 10.1016/0952-7915(92)90079-t

No coin nor oath required. For personal study only.

✦ Synopsis

Evidence has accumulated indicating that four T-cell derived lymphokines, interleukin-4, interleukin-5, granulocyte-macrophage colony stimulating factor and interleukin-3, are closely related. The genes encoding these lymphokines are clustered within a region of 1000 kb, the proteins have a common secondary and spatial organization, and their corresponding receptors are all members of the haemopoietin family of receptors.

📜 SIMILAR VOLUMES

Lymphokines and the immune response: the

Lymphokines and the immune response: the central role of interleukin-2

✍ Susan L. Swain 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 982 KB

A number of recent and past reports on the in vitro and in vivo roles of interleukin-2, interleukin-4, interferon-gamma and tumor necrosis factor-beta suggest that interleukin-2 plays a general role in the immune response. The other three lymphokines often play directive roles that determine the kin

Interleukin-4 differentially regulates i

Interleukin-4 differentially regulates interleukin-2-mediated and CD2-mediated induction of human lymphokine-activated killer effectors

✍ Eric Robinet; Malek Kamoun; Françoise Farace; Salem Chouaib 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 514 KB

The interleukin-1 family of molecules

✍ Anthony C. Allison 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 518 KB

Two types of interleukin I (IL-la and IL-IB) have been defined by purifying the molecules from activated human peripheral blood cells, followed by cloning and expressing the molecules in Escherichia coli. Both types of IL-1 stimulate proliferation and diferentiation of T-and B-lymphocytes and induce

Interleukin-6 enhances the induction of

Interleukin-6 enhances the induction of human lymphokine-activated killer cells

✍ G. Gallagher; W. H. Stimson; J. Findlay; F. Al-Azzawi 📂 Article 📅 1990 🏛 Springer-Verlag 🌐 English ⚖ 471 KB

Induction of lymphokine-activated killer

Induction of lymphokine-activated killer cells from nude mouse spleen cells by interleukin-4

✍ I. S. Tunru; H. Suzuki; M. Kobayashi 📂 Article 📅 1993 🏛 Springer 🌐 English ⚖ 380 KB

Functional interactions between interleu

Functional interactions between interleukin-4, interleukin-2, and tumor necrosis factor-al for lymphokine-activated killer cell generation

✍ Jean Yves Blay; Didier Branellec; Eric Robinet; Francoise Gay; Salem Chouaib 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 450 KB

## Abstract The purpose of the present study was to explore the interaction between interleukin‐2 (IL‐2), interleukin‐4 (IL‐4), and tumor necrosis factor‐a (TNF) on the differentiation of human large granular lymphocytes (LGL) into lymphokine‐activated killer cells (LAK). The data show that recombi