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Induction of lymphokine-activated killer cells from nude mouse spleen cells by interleukin-4

โœ Scribed by I. S. Tunru; H. Suzuki; M. Kobayashi


Publisher
Springer
Year
1993
Tongue
English
Weight
380 KB
Volume
49
Category
Article
ISSN
1420-682X

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Using a 4-h 51Cr release assay, we observed that thymocytes from Fischer strain rats incubated with recombinant human interleukin-2 (rhIL-2) developed cytotoxicity to YAC-1 lymphoma, 9L-glioma, and B-16 melanoma cells (effector/target ratio = 25/1). Induction of the lymphokine-activated killer (LAK)