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The interaction between bleomycin and radiation on cell survival and DNA damage in mammalian cell cultures

✍ Scribed by De-Zheng Wu; Yu-Qin Zhang; Peter Keng; Robert M. Sutherland; Louis Lasagna

Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
911 KB
Volume
11
Category
Article
ISSN
0360-3016

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## Abstract The effect of the anthracycline antibiotic, Adriamycin (Ad), on the sedimentation properties of pre‐labelled mammalian DNA has been studied. Ad induces DNA degradation __in vivo__ in both excision repair‐competent (HeLa and Me‐180) cells and in excision repair‐deficient (REQ) cells. Whe