## Abstract Microgel cell electrophoresis has been used with various species to measure breakage of DNA and DNA repair following exposure to the radiomimetic antibiotic, bleomycin. With humans, a high degree of DNA damage is considered to be predictive of cancer susceptibility. Non‐isogeneic __Xeno
DNA damage and repair induced by bleomycin in mammalian and insect cells
✍ Scribed by Néstor O. Bianchi; Daniel M. López-Larraza; V. L. Dellarco
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 518 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0893-6692
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Problems and Paradigms presents discussions and hypotheses of unsolved problems andpuzzles in biology. Two contributors are presented here. In the first, David T. Denhardt and Jacek Kowalski chart a possible relationship between DNA damage and an induced response to that damage in mammalian cells. I
1,4,6,8-Tetramethyl-2H-furo[2,3-h]quinolin-2-one [FQ] is an angelicin isoster characterized by a strong photosensitizing activity FQ shows a significant antiproliferative activity also in the dark, i.e., without UVA activation. The cytotoxic activity of FQ in the dark was detected in HeLa cells and
## Abstract DNA damage by agents crosslinking the strands presents a formidable challenge to the cell to repair for survival and to repair accurately for maintenance of genetic information. It appears that repair of DNA crosslinks occurs in a path involving double strand breaks (DSBs) in the DNA. M