The insulin-like growth factor-II/mannose-6-phosphate receptor: structure, distribution and function in the central nervous system
β Scribed by C Hawkes; S Kar
- Book ID
- 116327497
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 829 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0165-0173
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The soluble form of the insulin-like growth factor II (IGF-II)/mannose 6-P (IGF-II/ M6P) receptor is released by cells in culture and circulates in the serum. It retains its ability to bind IGF-II and blocks IGF-II-stimulated DNA synthesis in isolated rat hepatocytes. Because these cells are not nor
The ability of acute insulin treatment to elicit a redistribution of the liver insulin-like growth factor-II/ mannose 6-phosphate (IGF-II/M6P) receptor has been studied in rats, using cell fractionation. Injection of insulin (0.4 -50 g) led to a time-and dose-dependent decrease in IGF-II binding act