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Decreased expression of the mannose 6- phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cells

โœ Scribed by Zhihong Chen; Yinlin Ge; Natalie Landman; Jing X Kang


Book ID
115010476
Publisher
BioMed Central
Year
2002
Tongue
English
Weight
685 KB
Volume
2
Category
Article
ISSN
1471-2407

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Increased expression of the mannose 6-ph
โœ Jason S. Lee; Jocelyn Weiss; Janet L. Martin; Carolyn D. Scott ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 302 KB ๐Ÿ‘ 2 views

The mannose 6-phosphate/insulin-like growth factor-II receptor (M6P/IGF-IIR) is thought to act as a suppressor of tumor growth by binding the mitogenic peptide IGF-II and modulating its extracellular levels via degradation. This receptor has been found to be absent or nonfunctional in a high proport