Changes in the Expression of Insulin-like Growth Factor II/Mannose-6-phosphate Receptor during Endochondral Bone Development
β Scribed by Y.M. Yu; M.M. Sklar; S.P. Nissley; A.H. Reddi
- Book ID
- 115573452
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 535 KB
- Volume
- 195
- Category
- Article
- ISSN
- 0006-291X
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The ability of acute insulin treatment to elicit a redistribution of the liver insulin-like growth factor-II/ mannose 6-phosphate (IGF-II/M6P) receptor has been studied in rats, using cell fractionation. Injection of insulin (0.4 -50 g) led to a time-and dose-dependent decrease in IGF-II binding act