The influence of repeated treatment with imipramine, (+)- and (−)-oxaprotiline on behavioural effects of dopamine D-1 and D-2 agonists
✍ Scribed by J. Maj; M. Papp; G. Skuza; K. Bigajska; M. Zazula
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 759 KB
- Volume
- 76
- Category
- Article
- ISSN
- 1435-1463
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The ergoline derivative FCE 23884 acts as a dopamine D~1~ agonist in untreated parkinsonian animals and as a D~2~ antagonist in animals whose dopamine system is intact or levodopa treated. To evaluate whether this dual action might benefit patients with Parkinson's disease (PD) who have
The effects of selective D-2 and D-1 dopamine (DA) receptor agonists on food consumption were investigated in free-feeding rats. A selective D-2 receptor agonist, (+)-4-propyl-9-hydroxynaphthoxazine (PHNO), increased the consumption of standard food pellets in the dose range of 7.5-120 micrograms/kg
In hippocampal pyramidal cells (HPCs), Dopamine (DA) application (1 microM) produced, in 50% of recorded cells, an hyperpolarization of the resting membrane potential (r.m.p.) and an increase of the afterhyperpolarization (AHP) amplitude and duration in 79% of recorded cells. DA-induced effects on b
The effects of the dopamine (DA) receptor agonists apomorphine, bromocriptine and pergolide were compared with those produced by a DA receptor antagonist, haloperidol, in rats implanted with electrodes for chronic sleep recordings. Apomorphine (0.025-2.0 mg/kg) and bromocriptine (0.25-6.0 mg/kg) ind