Comparison of the effects of dopamine D 1 and D 2 receptor antagonists on rat striatal, limbic and nigral dopamine synthesis and utilisation
β Scribed by O. Magnusson; B. Mohringe; C. J. Fowler
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 741 KB
- Volume
- 69
- Category
- Article
- ISSN
- 1435-1463
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## Abstract In this study we examined the selectivity of dopamine (DA) for rat striatal DA D~1~ and D~2~ receptors. In a KrebsβHEPES buffer, the K~i~ values of DA for D~1~ binding sites (labelled with [^3^H]SCH23390) and D~2~ binding sites (labelled with [^3^H]spiroperidol) in striatal membranes am