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The Induction of DNA Strand Breaks in Normal Human Skin Fibroblasts Exposed to Solar Ultraviolet Radiation

✍ Scribed by Barry S. Rosenstein


Book ID
124656758
Publisher
Bioone
Year
1988
Tongue
English
Weight
700 KB
Volume
116
Category
Article
ISSN
0033-7587

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Induction of DNA strand breaks and DNAβ€”p
✍ Li-Wen Lai; Barry S. Rosenstein πŸ“‚ Article πŸ“… 1990 πŸ› Elsevier Science 🌐 English βš– 673 KB

Levels of DNA strand breaks and DNA-protein cross-links (DPCs) were measured using the alkaline elution assay in normal human skin fibroblasts irradiated with 0-200 J m-2 of 254 nm UV radiation and incubated for 0-24 h. On incubation, the yields of both single-strand breaks (SSBs) and DPCs increased