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The induction of cytochrome P-450 by isosafrole and related methylenedioxyphenyl compounds

โœ Scribed by Jon C. Cook; Ernest Hodgson


Book ID
114009339
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
913 KB
Volume
54
Category
Article
ISSN
0009-2797

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Differences in induction of hepatic cyto
โœ Lewandowski, Margaret ;Chui, Y. C. ;Levi, Patricia E. ;Hodgson, Ernest ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 900 KB

Eight methylenedioxyphenyl (MDP) compounds were examined for their ability to induce cytochrome P450 (P450) in mouse liver. Induction by safrole, isosafrole, and dihydrosafrole was studied in both C57BLl6N (Ah-responsive) and DBA/2N (Ahnonresponsive) male mice after IP administration of 200 mglkglda