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Differences in Induction of Three P450 Isozymes by Piperonyl Butoxide, Sesamex, Safrole, and Isosafrole

✍ Scribed by N.H. Adams; P.E. Levi; E. Hodgson


Book ID
118770067
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
921 KB
Volume
46
Category
Article
ISSN
0048-3575

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Differences in induction of hepatic cyto
✍ Lewandowski, Margaret ;Chui, Y. C. ;Levi, Patricia E. ;Hodgson, Ernest πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 900 KB

Eight methylenedioxyphenyl (MDP) compounds were examined for their ability to induce cytochrome P450 (P450) in mouse liver. Induction by safrole, isosafrole, and dihydrosafrole was studied in both C57BLl6N (Ah-responsive) and DBA/2N (Ahnonresponsive) male mice after IP administration of 200 mglkglda