Previous studies have documented the effects of 112 on the growth and effector function of tumor-infiltrating lymphocytes (TlL) in cancer patients. Since IL7 is known to induce Tand NK-cell responses in the peripheral blood, we examined the immuno-enhancing effects of 117 on TIL derived from human r
The in vitro effects of interleukin-12 upon tumor-infiltrating lymphocytes derived from renal cell carcinoma
✍ Scribed by Günther G. Steger; Michael F. Gnant; Manuela P. Djavanmard; Robert M. Mader; Raimund Jakesz; William Pierce; Jean B. deKernion; Robert Figlin; Arie Belldegrun
- Publisher
- Springer-Verlag
- Year
- 1997
- Tongue
- English
- Weight
- 865 KB
- Volume
- 123
- Category
- Article
- ISSN
- 1432-1335
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract It has been reported that in mice and in humans, tumor‐infiltrating lymphocytes (TIL) may exhibit a defect in CD3‐ζ‐chain expression. Therefore, the level of CD3‐ζ was analyzed in TIL derived from patients with renal‐cell carcinoma, and its correlation with TIL phenotype and function wa
## Renal-cell carcinoma (RCC ) is one of the human cancers which respond best to immunotherapy. To better characterize the mechanism of the immune response in RCC, we analyzed the T-cell receptor (TCR) p-chain repertoire in primary RCC, metastases and paired peripheral blood lymphocytes (PBL) from