The importance of cholesterol in maintenance of P-glycoprotein activity and its membrane perturbing influence
โ Scribed by Alice Rothnie; Daniel Theron; Loredana Soceneantu; Catherine Martin; Mounir Traikia; Georgina Berridge; Christopher F. Higgins; Philippe F. Devaux; Richard Callaghan
- Book ID
- 105947194
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 260 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1432-1017
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๐ SIMILAR VOLUMES
We have previously shown that amphiphilic diblock copolymers composed of methoxypolyethylene glycol-b-polycaprolactone (MePEG-b-PCL) increased the cellular accumulation and reduced the basolateral to apical flux of the P-glycoprotein substrate, rhodamine 123 (R-123) in caco-2 cells. The purpose of t
## Abstract Cyclinโdependent kinase 5 (Cdk5) is a unique member of the Cdk family; its kinase activity requires association with its activator, p35 or p39. p35 is the strongest and best characterized activator. Previous studies showed that p35 is a neuronโspecific protein that restricts Cdk5 activi