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The impact of family history on pathological and clinical outcomes in non-syndromic clear cell renal cell carcinoma

โœ Scribed by Matthew K. Tollefson; Stephen A. Boorjian; Christine M. Lohse; Michael L. Blute; Bradley C. Leibovich

Book ID
110922968
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
218 KB
Volume
106
Category
Article
ISSN
1464-4096

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โœ Hakimi, A. Ari; Chen, Ying-Bei; Wren, James; Gonen, Mithat; Abdel-Wahab, Omar; H ๐Ÿ“‚ Article ๐Ÿ“… 2013 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 704 KB

Background: Historically, VHL was the only frequently mutated gene in clear cell renal cell carcinoma (ccRCC), with conflicting clinical relevance. Recent sequencing efforts have identified several novel frequent mutations of histone modifying and chromatin remodeling genes in ccRCC including PBRM1,