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The immunological basis of tumor therapy by targeted delivery of TNFa to tumor vessels

✍ Scribed by Enrica Balza, Lorenzo Mortara, Francesca Sassi, Stefano Monteghirfo…

Book ID
120692952
Publisher
BioMed Central
Year
2006
Tongue
English
Weight
70 KB
Volume
3
Category
Article
ISSN
1742-4690

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## Abstract The irregular vasculature and high interstitial pressure of solid tumors hinder the delivery of cytotoxic agents to cancer cells. As a consequence, the doses of chemotherapy necessary to achieve complete tumor eradication are associated with unacceptably high toxicities. The selective t