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Tumor-targeted delivery of siRNA by non-viral vector: safe and effective cancer therapy

โœ Scribed by Chen, Yunching; Huang, Leaf

Book ID
120189514
Publisher
Informa plc
Year
2008
Tongue
English
Weight
336 KB
Volume
5
Category
Article
ISSN
1742-5247

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โœ Ping Mu; Shunji Nagahara; Naoki Makita; Yuzo Tarumi; Kenji Kadomatsu; Yoshifumi ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 816 KB

## Abstract The largest obstacle to the effective use of short interfering RNA (siRNA) in an animal body is the ability to deliver it to the target tissue. Here we showed a systemic delivery method of siRNA specific to pregrown solid tumors __via__ atelocollagen. Atelocollagen facilitated the selec