The immunocytochemical localization of neuronal nitric oxide synthase in the developing rat retina
โ Scribed by K.-Y. Kim; W.-K. Ju; S.-J. Oh; M.-H. Chun
- Publisher
- Springer-Verlag
- Year
- 2000
- Tongue
- English
- Weight
- 216 KB
- Volume
- 133
- Category
- Article
- ISSN
- 0014-4819
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The neuronal form of nitric oxide synthase (NOS-1) has been localized to several cell types in the retinas of experimental animals; however, localization in the human retina has not been definitive. By using in situ hybridization and immunohistochemistry, we have compared the cellular expression and
## Abstract Nitric oxide (NO) is a major signaling molecule in the retina and CNS, with physiological roles in every cell type in the retina. Previous work shows that neuronal nitric oxide synthase (nNOS) is an important source of NO in the vertebrate retina. There are distinct, active alternative