Immunocytochemical localisation of neuronal nitric oxide synthase in developing and transplanted rabbit retinas
โ Scribed by Rajesh K. Sharma; M.-T. R. Perez; Berndt Ehinger
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 638 KB
- Volume
- 107
- Category
- Article
- ISSN
- 1432-119X
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## Abstract Nitric oxide (NO) is a major signaling molecule in the retina and CNS, with physiological roles in every cell type in the retina. Previous work shows that neuronal nitric oxide synthase (nNOS) is an important source of NO in the vertebrate retina. There are distinct, active alternative
The neuronal form of nitric oxide synthase (NOS-1) has been localized to several cell types in the retinas of experimental animals; however, localization in the human retina has not been definitive. By using in situ hybridization and immunohistochemistry, we have compared the cellular expression and