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The i148mPnpla3polymorphism influences serum adiponectin in patients with fatty liver and healthy controls

โœ Scribed by Luca Valenti, Raffaela Rametta, Massimiliano Ruscica, Paola Dongiovanni, Liliana Steffani, Benedetta Maria Motta, Elena Canavesi, Anna Ludovica Fracanzani, Enrico Mozzi, Giancarlo Roviaro, Paolo Magni, Silvia Fargion


Book ID
119896054
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
345 KB
Volume
12
Category
Article
ISSN
1471-230X

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Inherited factors play a major role in the predisposition to nonalcoholic fatty liver disease (NAFLD), and the rs738409 CfiG polymorphism of PNPLA3/adiponutrin, encoding for the isoleucine-to-methionine substitution at residue 148 (I148M) protein variant, has recently been recognized as a major dete