F.N.39 HOMOZYGOSITY FOR THE PNPLA3/ADIPONUTRIN I148M POLYMORPHISM INFLUENCES LIVER FIBROSIS IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE
โ Scribed by L. Valenti; A. Al-Serri; A.K. Daly; E. Galmozzi; R. Rametta; P. Dongiovanni; V. Nobili; E. Mozzi; G. Roviaro; E. Vanni; E. Bugianesi; M. Maggioni; A.L. Fracanzani; S. Fargion; C.P. Day
- Book ID
- 119634087
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 42 KB
- Volume
- 42
- Category
- Article
- ISSN
- 1590-8658
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๐ SIMILAR VOLUMES
Inherited factors play a major role in the predisposition to nonalcoholic fatty liver disease (NAFLD), and the rs738409 CfiG polymorphism of PNPLA3/adiponutrin, encoding for the isoleucine-to-methionine substitution at residue 148 (I148M) protein variant, has recently been recognized as a major dete
The rising incidence of obesity and diabetes coincides with a marked increase in fructose consumption. Fructose consumption is higher in individuals with nonalcoholic fatty liver disease (NAFLD) than in age-matched and body mass index (BMI)-matched controls. Because fructose elicits metabolic pertur