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The human papillomavirus type 16 E6 oncogene induces premature mitotic chromosome segregation

โœ Scribed by Plug-Demaggio, Annemieke W; McDougall, James K


Book ID
110067047
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
381 KB
Volume
21
Category
Article
ISSN
0950-9232

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Human papillomavirus (HPV) DNA sequences are found in most carcinomas originating from the uterine cervix. HPV E6 and E7 oncogenes have been shown to cooperate with ras oncogenes to fully transform human epithelial cells. We investigated the effect of the Ha-ras oncogene on the transcriptional activ