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The human anti-CD30 antibody 5F11 shows in vitro and in vivo activity against malignant lymphoma

✍ Scribed by Borchmann, P.


Book ID
119973289
Publisher
American Society of Hematology
Year
2003
Tongue
English
Weight
274 KB
Volume
102
Category
Article
ISSN
0006-4971

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## Abstract CD19 is an attractive therapeutic target for treating human B‐cell tumors. In our study, chimeric (c) divalent (cHD37) and tetravalent (cHD37‐DcVV) anti‐CD19 monoclonal antibodies (MAbs) were constructed, expressed and evaluated for their binding to human 19‐positive (CD19^+^) tumor cel