𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A glycoengineered anti-CD19 antibody with potent antibody-dependent cellular cytotoxicity activity in vitro and lymphoma growth inhibition in vivo

✍ Scribed by Elizabeth Ward; Nanette Mittereder; Ellen Kuta; Gary P. Sims; Michael A. Bowen; William Dall’Acqua; Thomas Tedder; Peter Kiener; Anthony J. Coyle; Herren Wu; Bahija Jallal; Ronald Herbst

Book ID
108677432
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
984 KB
Volume
155
Category
Article
ISSN
0007-1048

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Chimeric, divalent and tetravalent anti-
Chimeric, divalent and tetravalent anti-CD19 monoclonal antibodies with potent in vitro and in vivo antitumor activity against human B-cell lymphoma and pre-B acute lymphoblastic leukemia cell lines
✍ Xiao-Yun Liu; Laurentiu M. Pop; Lydia Tsai; Iliodora V. Pop; Ellen S. Vitetta 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 295 KB

## Abstract CD19 is an attractive therapeutic target for treating human B‐cell tumors. In our study, chimeric (c) divalent (cHD37) and tetravalent (cHD37‐DcVV) anti‐CD19 monoclonal antibodies (MAbs) were constructed, expressed and evaluated for their binding to human 19‐positive (CD19^+^) tumor cel